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UAB Digital Repository of Documents 4 records found  Search took 0.01 seconds. 
1.
11 p, 1.9 MB The toxic effects of yeast Ppz1 phosphatase are counteracted by subcellular relocalization mediated by its regulatory subunit Hal3 / Albacar, Marcel (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Velázquez, Diego (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Casamayor Gracia, Antonio (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Ariño Carmona, Joaquín (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
Overexpression of Saccharomyces cerevisiae protein phosphatase Ppz1 strongly impairs cell growth. Ppz1 is negatively regulated by its subunit Hal3, and Hal3 overexpression fully counteracts the toxic effects derived from high levels of the phosphatase. [...]
2022 - 10.1002/1873-3468.14330
FEBS Letters, (March 2022)  
Detailed record - Creative Commons
2.
14 p, 1.2 MB Understanding oncogenicity of cancer driver genes and mutations in the cancer genomics era / Porta-Pardo, Eduard. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Valencia, A. (Institució Catalana de Recerca i Estudis Avançats) ; Godzik, A. (Division of Biomedical Sciences. University of California Riverside School of Medicine) ; Universitat Autònoma de Barcelona
One of the key challenges of cancer biology is to catalogue and understand the somatic genomic alterations leading to cancer. Although alternative definitions and search methods have been developed to identify cancer driver genes and mutations, analyses of thousands of cancer genomes return a remarkably similar catalogue of around 300 genes that are mutated in at least one cancer type. [...]
2020 - 10.1002/1873-3468.13781
FEBS Letters, Vol. 594 Núm. 24 (december 2020) , p. 4233-4246  
Detailed record - Creative Commons
3.
21 p, 3.4 MB NAADP mediates ATP-induced Ca2+ signals in astrocytes / Barceló Torns, Miquel (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Lewis, Alexander M. (University of Oxford) ; Gubern Burset, Albert (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Barneda, David (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Bloor-Young, Duncan (University of Oxford) ; Picatoste Ramón, Fernando (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Churchill, Grant C. (University of Oxford) ; Claro Izaguirre, Enrique (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Masgrau Juanola, Roser (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Intracellular Ca2+ signals provide astrocytes with a specific form of excitability that enables them to regulate synaptic transmission. In this study, we demonstrate that NAADP-AM, a membrane-permeant analogue of the new second messenger nicotinic acid-adenine dinucleotide phosphate (NAADP), mobilizes Ca2+ in astrocytes and that the response is blocked by Ned-19, an antagonist of NAADP signalling. [...]
2011 - 10.1016/j.febslet.2011.05.062
FEBS letters, Vol. 585, Num. 14 (2011) , p. 2300-2306  
Detailed record - Creative Commons
4.
6 p, 836.2 KB The presence of a high-Km hexokinase activity in dog, but not in boar, sperm / Fernández Novell, Josep M.. (Universitat de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Ballester i Casals, Joan (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ; Medrano, Antonio (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ; Otaegui Goya, Pedro José (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Rigau i Mas, Teresa (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ; Guinovart, Joan J. (Universitat de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Rodríguez Gil, Joan Enric (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)
The presence of a high-Km hexokinase activity was tested in both dog and boar spermatozoa. Hexokinase kinetics from dog extracts showed the presence of a specific activity (dog-sperm glucokinase-like protein, DSGLP), in the range of glucose concentrations of 4-10 mM, whereas boar sperm did not show any DSGLP activity. [...]
2004 - 10.1016/j.febslet.2004.06.015
FEBS letters, Vol. 570, Num. 1-3 (2004) , p. 211-216  
Detailed record -

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